Anti-h TSH 5405 SP-5
Catalog Number: 100819
Key Features
Liquid, may turn slightly opaque during storage
Human
LF, CLIA, FIA
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Key Documents
Product Overview
| Product Name | Anti-h TSH 5405 SP-5 |
|---|---|
| Catalog Number | 100819 |
| Description | Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components. |
| Application | LF, CLIA, FIA |
Further Specification
| Form/Appearance | Liquid, may turn slightly opaque during storage |
|---|---|
| Concentration | 5.0 mg/ml (+/- 10 %) |
| Notes | Wu et al. (2002) developed a three antibody assay system which utilizes clones 5403, 5404 and 5405. Clone 5405 was used as a coated antibody and clones 5403 and 5404 were used as biotinylated label antibodies. They were able to achieve 0.002 mIU/L analytical and 0.017 mIU/L functional sensitivity. The test had negligible cross-reactivity with LH, FSH and hCG which were tested up to 200 mIU/L and 2500 IU/L, respectively. |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Epitope | Group 3 |
| Purity | ≥ 95 % |
| Affinity constant | KA= 6.6 x 109 1/M; KD= 1.5 x 10-10 M (= 0.15 nM) |
| Associated Products | Native TSH antigen 996-51 |
| Buffer | 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| IEF Profile | 6.2–7.1 |
| Cross Reactivity | TSH α 9.3 %, hCG < 0.1 %, LH 0.47 %, FSH 1.8 % |
| Specificity | Antibody recognizes human thyrotropin and its free beta subunit |
Storage and Shipping
| Storage | +2-8°C |
|---|---|
| Shipping | Cold packs |
| Shelf Life | 36 months |
References
| References | Wu, F.-B., Han, S.-Q. and He, Y.-F. (2002) Time-resolved immunofluorometry of serum hTSH with enhanced sensitivity. J. Immunoassay & Immunochem., 23(2):191-210 |
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