Anti-hCG beta 5008 SP-5

Catalog Number: 100006

Key Features

Liquid, may turn slightly opaque during storage

Human

FIA

Following pairs are especially recommended for free hCG beta CLIA assays: (capture) – (detection)
hCG 5012 – hCG 5004
hCG 5012 – hCG 5008

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Key Documents

Product Overview
Product Name Anti-hCG beta 5008 SP-5
Catalog Number 100006
Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
Application FIA
Further Specification
Form/Appearance Liquid, may turn slightly opaque during storage
Concentration 5.0 mg/ml (+/- 10 %)
Isotype IgG1
Clonality Monoclonal
Epitope Beta-2 as described in Berger et al. (2013). The antibody recognizes both intact hCG and free β subunit.
Purity ≥ 95 %
Affinity constant hCG: KA= 2.9 x 1010 1/M; KD= 3.4 x 10-11 M (= 0.03 nM)
hCGb: KA= 4.4 x 109 1/M; KD= 2.3 x 10-10 M (= 0.23 nM)
Associated Products

Native hCG antigens, Lee Biosolutions 189-10 and 189-11
Native β-hCG antigen, Lee Biosolutions 325-11

Buffer 0.9 % NaCI, 0.095 % NaN3 as a preservative
IEF Profile 6.6 – 7.8
Cross Reactivity Does not recognize hCGα, LH, FSH, or TSH
Specificity Antibody recognizes human chorionic gonadotropin and its free beta subunit
Storage and Shipping
Storage +2-8°C
Shipping Cold packs
Shelf Life 36 months
References
References Berger, P., Paus, E., Hemken, P.M., Sturgeon, C., Stewart, W.W., Skinner, J.P., Harwick, L.C., Saldana, S.C., Ramsay, C.S., Rupprecht, K.R., Olsen, K.H., Bidart, J.M. and Stenman, U.H. (2013) Candidate epitopes for measurement of hCG and related molecules: the second ISOBM TD-7 workshop. Tumor Biol., 34: 4033-4057