Anti-Human CD130 Monoclonal Antibody, Azide Free Clone B-P8

Datasheet

Catalog Number: 852.080

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Key Features

Form :

Phosphate-buffered saline. Sterile-filtered through 0.22 µm. Carrier and preservative free

Host Species :

Mouse

Species Reactivity :

Human

Application :

ELISA, IP, Functional assay, IHC, FC

SKU Price(USD) Size Qty

852.080.000 $306.52 200µg / 200µl

Qty:

+ -

852.080.005 $450.00 500µg / 500µl

Qty:

+ -

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Product Overview

Product Name	Anti-Human CD130 Monoclonal Antibody, Azide Free Clone B-P8
Catalog Number	852.080
Description	Mouse monoclonal
Host Species	Mouse
Conjugation	Azide free
Application	ELISA, IP, Functional assay, IHC, FC
Immunogen	Natural soluble gp130

Further Specification

Form/Appearance	Phosphate-buffered saline. Sterile-filtered through 0.22 µm. Carrier and preservative free
Isotype	Mouse IgG1 Kappa light chain
Clonality	Monoclonal
Specificity	Recognises the Gp130, common subunit for IL-6, IL-11, OSM, LIF, CNTF, CT-1 receptors, a 130-140 kDa protein
Biological Activity	Inhibits CNTF activity and binding to gp130. Induces gp130 activation, Jak 1, Jak 2, Stat 1 and Stat 3 phosphorylation
Hybridoma	Myeloma X63/AG.8653 x Balb/c spleen cells

Storage and Shipping

Storage	Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
Shipping	Room Temperature

References

PubMed	Kurth, I. et al., J Immunol.,2000; 164(1): 273-82. - Pubmed link Gu, Z. J. et al., Leukemia,2000; 14(1): 188-97. - Pubmed link Müller-Newen G. et al., J. Biol. Chem., 2000; 275 (7) : 4578 - 4586 - Pubmed link Olivier, C. et al., J Biol Chem.,2000; 275(8): 5648-56. - Pubmed link Haan, C. et al., Biochem J.,2000; 349(Pt 1): 261-6 - Pubmed link Aoki, Y. et al., Blood,2001; 98(10): 3042-9. - Pubmed link Timmermann, A. et al., Eur J Biochem.,2002; 269(11): 2716-26. - Pubmed link Giese B. et al., J. Biol. Chem., 2003; 278(40) : 39205 - 39213 - Pubmed link Fischer, P. et al.,Biochem J.,2004;378(Pt 2): 449-60 - Pubmed link Giese, B. et al., J Cell Sci.,2005; 118(Pt 21): 5129-40. - Pubmed link Wijdenes J. et al., Eur. J. Immunol., 1995; 25(12): 3474-81 - Pubmed link Gu, Z. J. et al., J Immunol Methods,1996; 190(1): 21-7. - Pubmed link Chevalier, S. et al., J Biol Chem.,1996; 271(25): 14764-72. - Pubmed link Simpson, R. J. et al., Protein Sci.,1997; 6(5): 929-55. - Pubmed link Lebeau, B. et al., FEBS Lett.,1997; 407(2): 141-7. - Pubmed link Horsten, U. et al., J Biol Chem;,1997; 272(38): 23748-57. - Pubmed link Rebouissou C. et al., Blood, 1998; 91(12) : 4727 - 4737 - Pubmed link

PubMed

Kurth, I. et al., J Immunol.,2000; 164(1): 273-82. - Pubmed link
Gu, Z. J. et al., Leukemia,2000; 14(1): 188-97. - Pubmed link
Müller-Newen G. et al., J. Biol. Chem., 2000; 275 (7) : 4578 - 4586 - Pubmed link
Olivier, C. et al., J Biol Chem.,2000; 275(8): 5648-56. - Pubmed link
Haan, C. et al., Biochem J.,2000; 349(Pt 1): 261-6 - Pubmed link
Aoki, Y. et al., Blood,2001; 98(10): 3042-9. - Pubmed link
Timmermann, A. et al., Eur J Biochem.,2002; 269(11): 2716-26. - Pubmed link
Giese B. et al., J. Biol. Chem., 2003; 278(40) : 39205 - 39213 - Pubmed link
Fischer, P. et al.,Biochem J.,2004;378(Pt 2): 449-60 - Pubmed link
Giese, B. et al., J Cell Sci.,2005; 118(Pt 21): 5129-40. - Pubmed link
Wijdenes J. et al., Eur. J. Immunol., 1995; 25(12): 3474-81 - Pubmed link
Gu, Z. J. et al., J Immunol Methods,1996; 190(1): 21-7. - Pubmed link
Chevalier, S. et al., J Biol Chem.,1996; 271(25): 14764-72. - Pubmed link
Simpson, R. J. et al., Protein Sci.,1997; 6(5): 929-55. - Pubmed link
Lebeau, B. et al., FEBS Lett.,1997; 407(2): 141-7. - Pubmed link
Horsten, U. et al., J Biol Chem;,1997; 272(38): 23748-57. - Pubmed link
Rebouissou C. et al., Blood, 1998; 91(12) : 4727 - 4737 - Pubmed link